Perlane is commonly used for lip enhancement, wrinkle correction, moderate to severe facial folds, smile lines and thin superficial lines around the eyes, mouth and forehead.
Perlane is made by Medicis, which also makes the wrinkle filler Restylane. Both products contain hyaluronic acid.
Perlane's larger gel particles can reach the deep layers of the skin, offering enhanced volume and lifting power. Perlane has been used safely by dermatologists and plastic surgeons since 2000 outside the U.S.
According to Medicis, the maker of Perlane, the effects last for about six months.









