Testosterone Replacement , Andropause Testosterone Replacement Therapy for Testosterone Deficiency Enter zip code:   Similar to menopause in women, the condition affecting men with low testosterone in middle age is referred to as andropause. This syndrome has also been referred to as male climacteric, viropause, low-testosterone syndrome, androgen deficiency in the aging male (ADAM), partial androgen deficiency in the aging male (PADAM), and aging-associated androgen deficiency (AAAD). Testosterone replacement therapy can be prescribed in several forms. Your doctor may choose to treat testosterone deficiency through injection, skin patch, or a gel. The injections are delivered directly to the muscle and require regular visits. Testosterone replacement delivered transdermally involves a patch worn continuously. Gel testosterone is applied to the skin once each day. 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